| Uruguay Reserve League | 2022/03/29 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2020/11/03 18:00 | Boston River Reserves v Defensor Sporting Reserves | L | 2-1 |
| Uruguay Reserve League | 2019/11/11 19:00 | Boston River Reserves v Defensor Sporting Reserves | D | 1-1 |
| Uruguay Reserve League | 2019/04/07 16:15 | Defensor Sporting Reserves v Boston River Reserves | D | 0-0 |
| Uruguay Reserve League | 2018/05/02 18:00 | Defensor Sporting Reserves v Boston River Reserves | W | 3-2 |
| Uruguay Reserve League | 2017/11/20 13:00 | Boston River Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2016/09/01 17:48 | Boston River Reserves v Defensor Sporting Reserves | D | 0-0 |
| Uruguay Reserve League | 2022/07/25 18:00 | Liverpool Montevideo Reserves v Defensor Sporting Reserves | L | 3-1 |
| Uruguay Reserve League | 2022/06/14 18:00 | Rentistas Reserves v Defensor Sporting Reserves | L | 3-1 |
| Uruguay Reserve League | 2022/06/06 18:00 | Defensor Sporting Reserves v Deportivo Maldonado Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/05/31 18:00 | Danubio Reserves v Defensor Sporting Reserves | W | 0-3 |
| Uruguay Reserve League | 2022/05/26 17:00 | Albion FC Reserves v Defensor Sporting Reserves | L | 1-0 |
| Uruguay Reserve League | 2022/05/24 17:00 | Defensor Sporting Reserves v Nacional de Montevideo Reserves | L | 1-3 |
| Uruguay Reserve League | 2022/05/10 18:00 | Defensor Sporting Reserves v Cerrito Reserves | W | 3-1 |
| Uruguay Reserve League | 2022/05/02 18:00 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 0-2 |
| Uruguay Reserve League | 2022/08/23 14:00 | Boston River Reserves v Atletico River Plate Reserves | L | 2-3 |
| Uruguay Reserve League | 2022/08/08 18:00 | Cerrito Reserves v Boston River Reserves | W | 0-1 |
| Uruguay Reserve League | 2022/07/25 14:00 | Plaza Colonia Reserves v Boston River Reserves | W | 0-2 |
| Uruguay Reserve League | 2022/06/13 18:00 | Montevideo Wanderers Reserves v Boston River Reserves | L | 5-2 |
| Uruguay Reserve League | 2022/06/07 18:00 | Boston River Reserves v Torque Reserves | W | 2-1 |
| Uruguay Reserve League | 2022/05/30 18:00 | Penarol Reserves v Boston River Reserves | L | 2-1 |
| Uruguay Reserve League | 2022/05/23 18:00 | Boston River Reserves v Liverpool Montevideo Reserves | D | 1-1 |
| Uruguay Reserve League | 2022/05/19 18:00 | Rentistas Reserves v Boston River Reserves | L | 3-2 |