Stadium: Bryce Jordan Center
Home Manager: Micah Shrewsberry Away Manager: Tom Izzo
| NCAAB | 2022/02/16 00:00 | Michigan State v Penn State | L | 58-62 |
| NCAAB | 2021/12/11 19:00 | Penn State v Michigan State | W | 64-80 |
| NCAAB | 2021/02/10 00:00 | Penn State v Michigan State | W | 58-60 |
| NCAAB | 2020/03/04 00:00 | Michigan State v Penn State | W | 79-71 |
| NCAAB | 2020/02/05 01:00 | Penn State v Michigan State | L | 75-70 |
| NCAAB | 2019/01/13 21:30 | Michigan State v Penn State | W | 71-56 |
| NCAAB | 2018/01/31 23:30 | Penn State v Michigan State | W | 68-76 |
| NCAAB | 2017/03/09 19:40 | Penn State v Michigan State | W | 51-78 |
| NCAAB | 2022/03/20 21:15 | Michigan State v Duke | L | 76-85 |
| NCAAB | 2022/03/19 01:40 | Davidson v Michigan State | W | 73-74 |
| NCAAB | 2022/03/12 20:30 | Michigan State v Purdue | L | 70-75 |
| NCAAB | 2022/03/11 23:30 | Michigan State v Wisconsin | W | 69-63 |
| NCAAB | 2022/03/10 23:30 | Maryland v Michigan State | W | 72-76 |
| NCAAB | 2022/03/06 21:30 | Maryland v Michigan State | W | 67-77 |
| NCAAB | 2022/03/04 00:00 | Michigan State v Ohio State | L | 69-80 |
| NCAAB | 2022/03/02 01:30 | Michigan State v Michigan | L | 70-87 |
| NCAAB | 2022/03/12 02:00 | Penn State v Purdue | L | 61-69 |
| NCAAB | 2022/03/11 01:55 | Penn State v Ohio State | W | 71-68 |
| NCAAB | 2022/03/10 01:30 | Minnesota v Penn State | W | 51-60 |
| NCAAB | 2022/03/06 17:00 | Penn State v Rutgers | L | 58-59 |
| NCAAB | 2022/03/04 00:00 | Penn State v Illinois | L | 55-60 |
| NCAAB | 2022/02/28 00:00 | Nebraska v Penn State | L | 93-70 |
| NCAAB | 2022/02/26 00:00 | Northwestern v Penn State | W | 60-67 |
| NCAAB | 2022/02/22 00:00 | Penn State v Maryland | L | 61-67 |