Stadium: Jack Stephens Center
Home Manager: Darrell Walker Away Manager: Brian Barone
| NCAAB | 2022/03/03 00:30 | SIU Edwardsville v Tennessee State | L | 62-77 |
| NCAAB | 2022/02/26 21:30 | Morehead State v SIU Edwardsville | W | 70-77 |
| NCAAB | 2022/02/25 01:30 | Austin Peay v SIU Edwardsville | L | 68-64 |
| NCAAB | 2022/02/22 01:00 | Eastern Illinois v SIU Edwardsville | W | 52-66 |
| NCAAB | 2022/02/19 22:00 | SIU Edwardsville v Belmont | L | 62-73 |
| NCAAB | 2022/02/18 01:30 | SIU Edwardsville v Tennessee State | L | 65-81 |
| NCAAB | 2022/02/12 21:30 | Tennessee Tech v SIU Edwardsville | W | 60-61 |
| NCAAB | 2022/02/11 01:30 | Tennessee Martin v SIU Edwardsville | W | 63-71 |
| NCAAB | 2022/03/05 20:00 | Arkansas LR v Troy | L | 62-69 |
| NCAAB | 2022/03/03 20:00 | Arkansas LR v South Alabama | W | 75-71 |
| NCAAB | 2022/02/26 00:30 | Coastal Carolina v Arkansas LR | L | 68-55 |
| NCAAB | 2022/02/24 00:30 | Appalachian State v Arkansas LR | L | 78-66 |
| NCAAB | 2022/02/19 22:00 | Arkansas LR v Texas State | L | 50-68 |
| NCAAB | 2022/02/18 01:00 | Arkansas LR v UT Arlington | L | 70-85 |
| NCAAB | 2022/02/12 22:00 | Arkansas LR v Troy | W | 66-62 |
| NCAAB | 2022/02/11 01:00 | Arkansas LR v South Alabama | L | 46-77 |