Stadium: F. G. Clark Center
Home Manager: Johnny Jones Away Manager: Sean Woods
| NCAAB | 2022/02/15 01:30 | Southern v Texas Southern | L | 70-58 |
| NCAAB | 2022/01/04 01:30 | Texas Southern v Southern | L | 50-63 |
| NCAAB | 2021/03/06 21:00 | Southern v Texas Southern | W | 74-80 |
| NCAAB | 2020/03/06 01:30 | Texas Southern v Southern | L | 74-89 |
| NCAAB | 2020/01/05 01:30 | Southern v Texas Southern | W | 68-77 |
| NCAAB | 2019/03/13 00:30 | Southern v Texas Southern | W | 70-80 |
| NCAAB | 2019/03/10 01:30 | Southern v Texas Southern | L | 87-77 |
| NCAAB | 2019/01/08 01:30 | Texas Southern v Southern | W | 77-67 |
| NCAAB | 2022/03/18 01:57 | Texas Southern v Kansas | L | 56-83 |
| NCAAB | 2022/03/15 22:40 | Texas A&M Corpus v Texas Southern | W | 67-76 |
| NCAAB | 2022/03/12 23:00 | Texas Southern v Alcorn State | W | 87-62 |
| NCAAB | 2022/03/11 20:00 | Grambling State v Texas Southern | W | 54-73 |
| NCAAB | 2022/03/09 20:00 | Jackson State v Texas Southern | W | 50-54 |
| NCAAB | 2022/03/06 01:30 | Prairie View v Texas Southern | W | 77-78 |
| NCAAB | 2022/03/01 01:30 | Alcorn State v Texas Southern | L | 75-72 |
| NCAAB | 2022/02/27 01:30 | Jackson State v Texas Southern | W | 66-81 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | L | 60-58 |
| NCAAB | 2022/03/05 22:00 | Southern v Alabama A&M | W | 50-49 |
| NCAAB | 2022/03/04 02:00 | Southern v Alabama State | L | 67-77 |
| NCAAB | 2022/03/01 02:00 | Florida A&M v Southern | W | 49-58 |
| NCAAB | 2022/02/26 23:30 | Bethune Cookman v Southern | L | 87-84 |
| NCAAB | 2022/02/19 22:30 | Grambling State v Southern | L | 61-57 |
| NCAAB | 2022/02/15 01:30 | Southern v Texas Southern | W | 70-58 |
| NCAAB | 2022/02/12 23:30 | Southern v Prairie View | L | 77-84 |