Stadium: War Memorial Gymnasium
Home Manager: Herb Sendek Away Manager: Chris Gerlufsen
| NCAAB | 2022/02/12 23:00 | San Francisco v Santa Clara | L | 74-58 |
| NCAAB | 2022/01/30 00:00 | Santa Clara v San Francisco | L | 85-88 |
| NCAAB | 2021/01/22 03:00 | San Francisco v Santa Clara | L | 73-50 |
| NCAAB | 2020/02/14 02:00 | San Francisco v Santa Clara | L | 70-61 |
| NCAAB | 2020/01/10 04:00 | Santa Clara v San Francisco | L | 61-80 |
| NCAAB | 2019/02/24 04:00 | San Francisco v Santa Clara | W | 65-68 |
| NCAAB | 2019/02/10 04:00 | Santa Clara v San Francisco | L | 72-78 |
| NCAAB | 2018/02/04 04:00 | San Francisco v Santa Clara | L | 70-59 |
| NIT | 2022/03/16 03:00 | Santa Clara v Washington State | L | 50-63 |
| NCAAB | 2022/03/08 04:30 | Santa Clara v Saint Mary's CA | L | 72-75 |
| NCAAB | 2022/03/06 05:30 | Portland v Santa Clara | W | 67-91 |
| NCAAB | 2022/02/26 22:00 | Portland v Santa Clara | W | 89-102 |
| NCAAB | 2022/02/25 03:00 | Santa Clara v Pepperdine | W | 89-73 |
| NCAAB | 2022/02/20 02:00 | Santa Clara v Gonzaga | L | 69-81 |
| NCAAB | 2022/02/17 08:27 | Santa Clara v Loyola Marymount | W | 84-80 |
| NCAAB | 2022/02/12 23:00 | San Francisco v Santa Clara | L | 74-58 |
| NCAAB | 2022/03/18 01:40 | San Francisco v Murray State | L | 87-92 |
| NCAAB | 2022/03/08 02:00 | San Francisco v Gonzaga | L | 71-81 |
| NCAAB | 2022/03/06 03:30 | BYU v San Francisco | W | 63-75 |
| NCAAB | 2022/02/26 22:00 | San Francisco v San Diego | W | 78-62 |
| NCAAB | 2022/02/25 02:00 | Gonzaga v San Francisco | L | 89-73 |
| NCAAB | 2022/02/22 02:00 | San Francisco v Pacific | W | 104-71 |
| NCAAB | 2022/02/18 03:00 | San Francisco v Saint Mary's CA | L | 64-69 |
| NCAAB | 2022/02/12 23:00 | San Francisco v Santa Clara | W | 74-58 |