Stadium: Tom Gola Arena
Home Manager: Fran Dunphy Away Manager: Frank Martin
| NCAAB | 2022/02/19 17:00 | La Salle v Massachusetts | W | 74-80 |
| NCAAB | 2022/01/27 00:00 | Massachusetts v La Salle | W | 77-71 |
| NCAAB | 2021/01/09 21:00 | La Salle v Massachusetts | W | 67-83 |
| NCAAB | 2020/12/16 17:00 | Massachusetts v La Salle | W | 85-66 |
| NCAAB | 2020/03/05 00:00 | Massachusetts v La Salle | W | 75-64 |
| NCAAB | 2020/01/09 00:00 | La Salle v Massachusetts | W | 69-77 |
| NCAAB | 2019/01/31 00:00 | Massachusetts v La Salle | L | 51-60 |
| NCAAB | 2019/01/05 18:00 | La Salle v Massachusetts | L | 69-60 |
| NCAAB | 2022/03/11 23:00 | Massachusetts v Dayton | L | 72-75 |
| NCAAB | 2022/03/10 23:00 | Massachusetts v George Washington | W | 99-88 |
| NCAAB | 2022/03/05 21:00 | Massachusetts v George Mason | W | 83-80 |
| NCAAB | 2022/03/03 00:00 | Fordham v Massachusetts | W | 73-81 |
| NCAAB | 2022/03/01 00:00 | Massachusetts v Fordham | L | 73-85 |
| NCAAB | 2022/02/26 21:30 | VA Commonwealth v Massachusetts | L | 77-62 |
| NCAAB | 2022/02/24 00:00 | Massachusetts v Dayton | L | 61-82 |
| NCAAB | 2022/02/19 17:00 | La Salle v Massachusetts | W | 74-80 |
| Peru Liga Nacional | 2022/10/20 23:00 | Regatas de Lima v La Salle | L | 74-69 |
| NCAAB | 2022/03/10 19:30 | La Salle v St Louis | L | 51-71 |
| NCAAB | 2022/03/09 18:00 | St Josephs v La Salle | W | 56-63 |
| NCAAB | 2022/03/05 19:00 | La Salle v Duquesne | W | 85-76 |
| NCAAB | 2022/03/03 00:00 | St Josephs v La Salle | W | 48-49 |
| NCAAB | 2022/02/26 19:00 | Dayton v La Salle | W | 60-62 |
| NCAAB | 2022/02/24 00:00 | La Salle v Fordham | L | 54-60 |
| NCAAB | 2022/02/19 17:00 | La Salle v Massachusetts | L | 74-80 |