Stadium: Knapp Center
Home Manager: Ryan Pedon Away Manager: Darian DeVries
| NCAAB | 2022/01/27 01:00 | Drake v Illinois St | L | 89-88 |
| NCAAB | 2022/01/13 01:00 | Illinois St v Drake | L | 75-86 |
| NCAAB | 2021/02/02 00:00 | Illinois St v Drake | L | 60-95 |
| NCAAB | 2021/01/31 20:00 | Illinois St v Drake | L | 76-78 |
| NCAAB | 2020/03/06 00:05 | Illinois St v Drake | L | 65-75 |
| NCAAB | 2020/02/22 21:30 | Drake v Illinois St | W | 53-57 |
| NCAAB | 2020/01/17 01:00 | Illinois St v Drake | L | 74-84 |
| NCAAB | 2019/03/09 00:00 | Illinois St v Drake | L | 62-78 |
| NCAAB | 2022/03/04 18:00 | Illinois St v Northern Iowa | L | 65-78 |
| NCAAB | 2022/03/04 00:00 | Indiana State v Illinois St | W | 53-58 |
| NCAAB | 2022/02/26 21:00 | Indiana State v Illinois St | W | 66-86 |
| NCAAB | 2022/02/24 01:00 | Illinois St v Southern Illinois | L | 69-90 |
| NCAAB | 2022/02/22 01:00 | Loyola Chicago v Illinois St | L | 59-50 |
| NCAAB | 2022/02/19 19:00 | Illinois St v Bradley | L | 64-72 |
| NCAAB | 2022/02/16 01:00 | Northern Iowa v Illinois St | L | 72-70 |
| NCAAB | 2022/02/12 18:00 | Illinois St v Indiana State | L | 57-60 |
| CBI | 2022/03/21 17:00 | Drake v UNC Wilmington | L | 75-76 |
| CBI | 2022/03/19 16:00 | IPFW v Drake | W | 65-87 |
| NCAAB | 2022/03/06 19:00 | Loyola Chicago v Drake | L | 64-58 |
| NCAAB | 2022/03/05 23:00 | Drake v Missouri State | W | 79-78 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | W | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | W | 60-62 |
| NCAAB | 2022/02/24 00:00 | Drake v Valparaiso | W | 71-65 |
| NCAAB | 2022/02/22 01:00 | Indiana State v Drake | W | 58-74 |