Stadium: Kirby Sports Center
Home Manager: Mike Jordan Away Manager: Tavaras Hardy
| NCAAB | 2022/02/17 00:00 | Loyola Maryland v Lafayette | L | 68-77 |
| NCAAB | 2022/01/14 00:00 | Lafayette v Loyola Maryland | W | 60-74 |
| NCAAB | 2021/02/14 22:00 | Lafayette v Loyola Maryland | W | 69-88 |
| NCAAB | 2021/02/13 19:00 | Loyola Maryland v Lafayette | L | 94-97 |
| NCAAB | 2021/02/09 00:00 | Loyola Maryland v Lafayette | L | 76-80 |
| NCAAB | 2021/02/07 17:00 | Lafayette v Loyola Maryland | W | 62-75 |
| NCAAB | 2021/01/17 23:00 | Lafayette v Loyola Maryland | L | 72-70 |
| NCAAB | 2021/01/16 21:00 | Loyola Maryland v Lafayette | L | 75-77 |
| NCAAB | 2022/03/04 00:00 | Loyola Maryland v Boston U | L | 64-76 |
| NCAAB | 2022/02/26 19:00 | Loyola Maryland v American | L | 55-65 |
| NCAAB | 2022/02/24 00:00 | Loyola Maryland v Navy | L | 50-52 |
| NCAAB | 2022/02/20 22:00 | Lehigh v Loyola Maryland | W | 42-69 |
| NCAAB | 2022/02/17 00:00 | Loyola Maryland v Lafayette | L | 68-77 |
| NCAAB | 2022/02/12 22:00 | Colgate v Loyola Maryland | L | 64-56 |
| NCAAB | 2022/02/10 00:00 | Loyola Maryland v Holy Cross | L | 64-68 |
| NCAAB | 2022/02/05 22:00 | Navy v Loyola Maryland | L | 56-55 |
| NCAAB | 2022/03/02 00:00 | Bucknell v Lafayette | L | 82-81 |
| NCAAB | 2022/02/26 19:00 | Lehigh v Lafayette | L | 78-58 |
| NCAAB | 2022/02/24 00:00 | Lafayette v Boston U | L | 60-76 |
| NCAAB | 2022/02/22 00:00 | Holy Cross v Lafayette | W | 61-84 |
| NCAAB | 2022/02/19 21:00 | Lafayette v Bucknell | L | 89-92 |
| NCAAB | 2022/02/17 00:00 | Loyola Maryland v Lafayette | W | 68-77 |
| NCAAB | 2022/02/14 23:00 | Lafayette v Colgate | L | 61-69 |
| NCAAB | 2022/02/12 17:00 | Lafayette v Lehigh | W | 73-69 |