Stadium: Memorial Hall Bayhealth Court
Home Manager: Danielle Santos Atkinson Away Manager: Yconda Hill
| WNCAAB | 2022/03/11 17:00 | Hofstra (W) v Drexel Women | L | 39-60 |
| WNCAAB | 2022/03/10 19:00 | Hofstra (W) v UNC Wilmington (W) | W | 46-45 |
| WNCAAB | 2022/03/05 18:00 | Hofstra (W) v UNC Wilmington (W) | W | 67-52 |
| WNCAAB | 2022/03/04 00:00 | Hofstra (W) v Coll of Charleston (W) | L | 35-75 |
| WNCAAB | 2022/02/27 19:00 | James Madison (W) v Hofstra (W) | L | 68-63 |
| WNCAAB | 2022/02/26 00:00 | Towson (W) v Hofstra (W) | L | 73-50 |
| WNCAAB | 2022/02/24 00:00 | Coll of Charleston (W) v Hofstra (W) | W | 61-73 |
| WNCAAB | 2022/02/20 19:00 | Hofstra (W) v William & Mary (W) | L | 48-61 |
| WNCAAB | 2022/03/09 17:00 | Delaware State (W) v Howard (W) | L | 51-87 |
| WNCAAB | 2022/03/03 22:30 | Delaware State (W) v Maryland Eastern Shore (W) | L | 48-66 |
| WNCAAB | 2022/02/28 22:30 | Coppin State (W) v Delaware State (W) | L | 67-55 |
| WNCAAB | 2022/02/26 19:00 | Morgan State (W) v Delaware State (W) | L | 69-63 |
| WNCAAB | 2022/02/21 22:30 | South Carolina State (W) v Delaware State (W) | L | 64-52 |
| WNCAAB | 2022/02/19 19:00 | Delaware State (W) v North Carolina Central (W) | L | 49-73 |
| WNCAAB | 2022/02/16 22:00 | Delaware State (W) v Morgan State (W) | L | 42-67 |
| WNCAAB | 2022/02/14 22:30 | Norfolk State (W) v Delaware State (W) | L | 76-31 |