Stadium: Hulman Center
Home Manager: Andrea Williams Away Manager: Chad Killinger
| WNCAAB | 2022/03/05 18:00 | Chicago State (W) v Seattle Women | L | 54-57 |
| WNCAAB | 2022/03/03 00:00 | California Baptist (W) v Chicago State (W) | L | 76-69 |
| WNCAAB | 2022/02/26 19:00 | Chicago State (W) v New Mexico State (W) | L | 71-80 |
| WNCAAB | 2022/02/25 01:00 | Chicago State (W) v Grand Canyon (W) | L | 55-73 |
| WNCAAB | 2022/02/19 20:00 | Chicago State (W) v Tarleton State (W) | L | 51-65 |
| WNCAAB | 2022/02/17 00:00 | Stephen F. Austin (W) v Chicago State (W) | L | 73-49 |
| WNCAAB | 2022/02/12 21:00 | Chicago State (W) v Sam Houston State (W) | L | 58-61 |
| WNCAAB | 2022/02/11 00:30 | Chicago State (W) v Stephen F. Austin (W) | L | 55-84 |
| WNCAAB | 2022/03/11 18:00 | Indiana State (W) v Southern Illinois (W) | L | 61-77 |
| WNCAAB | 2022/03/10 22:00 | Indiana State (W) v Evansville (W) | W | 89-75 |
| WNCAAB | 2022/03/05 18:00 | Drake (W) v Indiana State (W) | L | 86-71 |
| WNCAAB | 2022/03/03 23:00 | Northern Iowa (W) v Indiana State (W) | L | 61-55 |
| WNCAAB | 2022/02/26 20:00 | Indiana State (W) v Missouri State (W) | L | 65-72 |
| WNCAAB | 2022/02/25 00:00 | Indiana State (W) v Southern Illinois (W) | L | 46-63 |
| WNCAAB | 2022/02/20 18:00 | Valparaiso Women v Indiana State (W) | L | 74-69 |
| WNCAAB | 2022/02/18 23:00 | Loyola Chicago (W) v Indiana State (W) | L | 61-59 |