[21] NY Islanders 1-2 OTT Senators [25] 2022-09-02 04:00
Stadium: Canadian Tire Centre
Home Manager: Away Manager: Lane Lambert
Head to Head
| NHL | 2022/03/22 23:30 | OTT Senators v NY Islanders | W | 0-3 |
| NHL | 2022/02/02 00:30 | OTT Senators v NY Islanders | W | 1-4 |
| NHL | 2021/12/08 00:00 | NY Islanders v OTT Senators | W | 5-3 |
| NHL | 2020/03/06 00:30 | NY Islanders v OTT Senators | L | 3-4 |
| NHL | 2019/11/06 00:00 | OTT Senators v NY Islanders | W | 1-4 |
| NHL | 2019/10/25 23:30 | NY Islanders v OTT Senators | W | 4-2 |
| NHL | 2019/03/08 00:30 | NY Islanders v OTT Senators | W | 4-2 |
| NHL | 2019/03/06 00:00 | OTT Senators v NY Islanders | W | 4-5 |
Home History
| NHL | 2022/04/29 23:30 | TB Lightning v NY Islanders | L | 6-4 |
| NHL | 2022/04/28 23:00 | WAS Capitals v NY Islanders | W | 1-5 |
| NHL | 2022/04/26 23:00 | NY Islanders v WAS Capitals | W | 4-1 |
| NHL | 2022/04/24 17:00 | CAR Hurricanes v NY Islanders | L | 5-2 |
| NHL | 2022/04/23 16:30 | NY Islanders v BUF Sabres | L | 3-5 |
| NHL | 2022/04/21 23:30 | NY Rangers v NY Islanders | L | 6-3 |
| NHL | 2022/04/19 23:30 | FLA Panthers v NY Islanders | L | 3-2 |
| NHL | 2022/04/17 23:30 | NY Islanders v TOR Maple Leafs | L | 2-4 |
Away History
| NHL | 2022/04/29 23:00 | OTT Senators v PHI Flyers | W | 4-2 |
| NHL | 2022/04/28 23:00 | FLA Panthers v OTT Senators | L | 4-0 |
| NHL | 2022/04/26 23:00 | NJ Devils v OTT Senators | W | 4-5 |
| NHL | 2022/04/23 23:00 | MTL Canadiens v OTT Senators | W | 4-6 |
| NHL | 2022/04/22 23:00 | OTT Senators v CLB Blue Jackets | W | 2-1 |
| NHL | 2022/04/20 02:00 | OTT Senators v VAN Canucks | W | 4-3 |
| NHL | 2022/04/19 02:00 | OTT Senators v SEA Kraken | L | 2-4 |
| NHL | 2022/04/16 23:00 | TOR Maple Leafs v OTT Senators | L | 5-4 |