[15] OTT Senators 4-2 BUF Sabres [16] 2018-03-20 23:30
Stadium: KeyBank Center Round: 1
Home Manager: Guy Boucher Away Manager: Phil Housley
Head to Head
| NHL | 2018/03/09 00:30 | BUF Sabres v OTT Senators | L | 4-3 |
| NHL | 2018/02/16 00:30 | BUF Sabres v OTT Senators | W | 2-3 |
| NHL | 2017/12/13 00:00 | OTT Senators v BUF Sabres | L | 2-3 |
| NHL | 2017/02/15 00:30 | BUF Sabres v OTT Senators | L | 3-2 |
| NHL | 2017/02/05 00:00 | OTT Senators v BUF Sabres | L | 0-4 |
| NHL | 2016/11/30 00:30 | BUF Sabres v OTT Senators | L | 5-4 |
| NHL | 2016/11/10 00:30 | OTT Senators v BUF Sabres | W | 2-1 |
| NHL | 2016/11/05 23:00 | BUF Sabres v OTT Senators | L | 2-1 |
Home History
| NHL | 2018/03/17 23:00 | OTT Senators v CLB Blue Jackets | L | 1-2 |
| NHL | 2018/03/16 23:30 | DAL Stars v OTT Senators | W | 2-3 |
| NHL | 2018/03/13 23:30 | OTT Senators v TB Lightning | W | 7-4 |
| NHL | 2018/03/12 23:30 | OTT Senators v FLA Panthers | W | 5-3 |
| NHL | 2018/03/10 00:30 | CGY Flames v OTT Senators | L | 2-1 |
| NHL | 2018/03/09 00:30 | BUF Sabres v OTT Senators | L | 4-3 |
| NHL | 2018/03/06 01:30 | OTT Senators v DAL Stars | W | 3-2 |
| NHL | 2018/03/04 01:00 | OTT Senators v ARZ Coyotes | L | 1-2 |
Away History
| NHL | 2018/03/19 23:00 | NSH Predators v BUF Sabres | L | 4-0 |
| NHL | 2018/03/17 17:00 | CHI Blackhawks v BUF Sabres | W | 3-5 |
| NHL | 2018/03/15 23:00 | TOR Maple Leafs v BUF Sabres | L | 5-2 |
| NHL | 2018/03/10 18:00 | VGS Golden Knights v BUF Sabres | L | 2-1 |
| NHL | 2018/03/09 00:30 | BUF Sabres v OTT Senators | W | 4-3 |
| NHL | 2018/03/08 00:30 | CGY Flames v BUF Sabres | L | 5-1 |
| NHL | 2018/03/06 00:30 | TOR Maple Leafs v BUF Sabres | W | 3-5 |
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | L | 1-4 |