| Copa Libertadores Women | 2022/10/19 20:00 | Club Nanas Women v Defensor Sporting (W) | L | 4-3 |
| Copa Libertadores Women | 2022/10/16 22:15 | Defensor Sporting (W) v Ferroviaria (W) | L | 0-1 |
| Copa Libertadores Women | 2022/10/13 20:00 | Defensor Sporting (W) v Boca Juniors (W) | L | 0-2 |
| Uruguay League Women | 2022/10/02 00:00 | Nacional De Football (W) v Defensor Sporting (W) | L | 2-0 |
| Uruguay League Women | 2022/09/18 18:30 | Defensor Sporting (W) v Liverpool Montevideo (W) | W | 3-0 |
| Uruguay League Women | 2022/09/11 16:30 | CA River Plate Women v Defensor Sporting (W) | W | 1-2 |
| Uruguay League Women | 2022/07/17 13:30 | Liverpool Montevideo (W) v Defensor Sporting (W) | D | 2-2 |
| Uruguay League Women | 2022/07/10 18:00 | Defensor Sporting (W) v CA River Plate Women | W | 6-2 |