[12] Purdue 15-23 Northwestern [5] 2023-09-08 21:00
Stadium: Ryan Field Round: 1
Home Manager: Ryan Walters Away Manager: David Braun
Head to Head
| NCAAF | 2022/11/19 17:00 | Northwestern v Purdue | W | 9-17 |
| NCAAF | 2021/11/20 17:00 | Purdue v Northwestern | W | 32-14 |
| NCAAF | 2020/11/14 22:00 | Northwestern v Purdue | L | 27-20 |
| NCAAF | 2019/11/09 17:00 | Purdue v Northwestern | W | 24-22 |
| NCAAF | 2018/08/31 00:00 | Northwestern v Purdue | L | 31-27 |
| NCAAF | 2017/11/12 00:00 | Purdue v Northwestern | L | 13-23 |
| NCAAF | 2016/11/12 17:00 | Northwestern v Purdue | L | 45-17 |
| NCAAF | 2015/11/14 17:00 | Northwestern v Purdue | L | 21-14 |
Home History
| NCAAF | 2023/09/02 16:00 | Fresno State v Purdue | L | 39-35 |
| NCAAF Bowl Games | 2023/01/02 18:00 | Purdue v LSU | L | 7-63 |
| NCAAF | 2022/12/04 01:00 | Purdue v Michigan | L | 22-43 |
| NCAAF | 2022/11/26 20:30 | Purdue v Indiana | W | 30-16 |
| NCAAF | 2022/11/19 17:00 | Northwestern v Purdue | W | 9-17 |
| NCAAF | 2022/11/12 17:00 | Purdue v Illinois | W | 31-24 |
| NCAAF | 2022/11/05 16:00 | Iowa v Purdue | L | 24-3 |
| NCAAF | 2022/10/22 19:30 | Purdue v Wisconsin | L | 24-35 |
Away History
| NCAAF | 2023/09/03 16:00 | Northwestern v Rutgers | L | 7-24 |
| NCAAF | 2022/11/26 20:30 | Illinois v Northwestern | L | 41-3 |
| NCAAF | 2022/11/19 17:00 | Northwestern v Purdue | L | 9-17 |
| NCAAF | 2022/11/12 20:30 | Northwestern v Minnesota | L | 3-31 |
| NCAAF | 2022/11/05 16:00 | Ohio State v Northwestern | L | 21-7 |
| NCAAF | 2022/10/29 19:30 | Northwestern v Iowa | L | 13-33 |
| NCAAF | 2022/10/22 19:30 | Northwestern v Maryland | L | 24-31 |
| NCAAF | 2022/10/08 19:30 | Wisconsin v Northwestern | L | 42-7 |