Stadium: Shuford Stadium Round: 1
| NCAAF | 2022/11/12 18:00 | Catawba College v Carson–Newman Eagles | L | 23-61 |
| NCAAF | 2022/11/05 18:00 | Catawba College v Lenoir Rhyne Bears | L | 10-62 |
| NCAAF | 2022/10/29 18:00 | Barton Bulldogs v Catawba College | L | 38-21 |
| NCAAF | 2022/10/22 22:00 | Catawba College v Limestone Saints | L | 23-48 |
| NCAAF | 2022/10/15 22:00 | Catawba College v Newberry Wolves | L | 27-34 |
| NCAAF | 2022/10/08 22:00 | Wingate Bulldogs v Catawba College | L | 28-0 |
| NCAAF | 2022/09/30 19:00 | Emory And Henry Wasps v Catawba College | L | 38-23 |
| NCAAF | 2022/09/24 20:00 | Catawba College v Tusculum Pioneers | L | 17-50 |
| NCAAF | 2022/11/12 17:00 | Limestone Saints v Emory And Henry Wasps | L | 45-27 |
| NCAAF | 2022/11/05 20:00 | Erskine Flying Fleet v Emory And Henry Wasps | W | 0-32 |
| NCAAF | 2022/10/29 17:00 | Emory And Henry Wasps v Carson–Newman Eagles | L | 7-21 |
| NCAAF | 2022/10/22 17:30 | Tusculum Pioneers v Emory And Henry Wasps | L | 35-9 |
| NCAAF | 2022/10/15 17:30 | Mars Hill Lions v Emory And Henry Wasps | L | 49-14 |
| NCAAF | 2022/10/08 17:00 | Emory And Henry Wasps v Virginia Wise Highland Cavaliers | W | 34-14 |
| NCAAF | 2022/09/30 19:00 | Emory And Henry Wasps v Catawba College | W | 38-23 |
| NCAAF | 2022/09/24 22:00 | Wingate Bulldogs v Emory And Henry Wasps | W | 10-17 |