Stadium: DICK'S SPORTING GOODS FIELD Round: 1
| NCAAF | 2022/10/29 16:00 | Edinboro v Seton Hill Griffins | W | 14-45 |
| NCAAF | 2021/10/02 20:00 | Seton Hill Griffins v Edinboro | L | 7-17 |
| NCAAF | 2019/10/26 16:00 | Seton Hill Griffins v Edinboro | L | 10-37 |
| NCAAF | 2018/10/20 16:00 | Edinboro v Seton Hill Griffins | L | 56-12 |
| NCAAF | 2022/11/12 17:00 | Seton Hill Griffins v Millersville University of Pennsylvania Marauders | L | 10-14 |
| NCAAF | 2022/11/05 18:00 | Seton Hill Griffins v Mercyhurst | W | 7-0 |
| NCAAF | 2022/10/29 16:00 | Edinboro v Seton Hill Griffins | W | 14-45 |
| NCAAF | 2022/10/22 18:00 | Iup Crimson Hawks v Seton Hill Griffins | L | 44-7 |
| NCAAF | 2022/10/15 22:00 | Seton Hill Griffins v California Vulcans | L | 14-21 |
| NCAAF | 2022/10/08 20:00 | Seton Hill Griffins v Clarion Golden Eagles | L | 13-40 |
| NCAAF | 2022/10/01 16:00 | Gannon University Golden Knights v Seton Hill Griffins | L | 21-10 |
| NCAAF | 2022/09/24 22:00 | Slippery Rock v Seton Hill Griffins | L | 30-2 |
| NCAAF | 2022/11/12 17:00 | Edinboro v Lock Haven | W | 26-13 |
| NCAAF | 2022/11/05 17:00 | Slippery Rock v Edinboro | L | 28-21 |
| NCAAF | 2022/10/29 16:00 | Edinboro v Seton Hill Griffins | L | 14-45 |
| NCAAF | 2022/10/22 16:00 | Clarion Golden Eagles v Edinboro | W | 17-47 |
| NCAAF | 2022/10/15 16:00 | Edinboro v Iup Crimson Hawks | L | 0-41 |
| NCAAF | 2022/10/08 18:00 | Edinboro v Gannon University Golden Knights | L | 17-35 |
| NCAAF | 2022/10/01 18:00 | Mercyhurst v Edinboro | W | 13-16 |
| NCAAF | 2022/09/24 16:00 | California Vulcans v Edinboro | L | 49-7 |