Stadium: Carl W. Burt Memorial Stadium Round: 1
| NCAAF | 2022/11/05 17:30 | Defiance Yellow Jackets v Manchester Spartans | L | 24-21 |
| NCAAF | 2021/10/09 17:30 | Manchester Spartans v Defiance Yellow Jackets | W | 22-0 |
| NCAAF | 2019/11/09 18:30 | Defiance Yellow Jackets v Manchester Spartans | W | 0-19 |
| NCAAF | 2019/09/19 23:00 | Manchester Spartans v Defiance Yellow Jackets | W | 52-21 |
| NCAAF | 2018/09/15 22:00 | Manchester Spartans v Defiance Yellow Jackets | W | 57-26 |
| NCAAF | 2023/09/09 20:00 | Manchester Spartans v Alma College Scots | L | 0-68 |
| NCAAF | 2023/09/02 22:00 | Manchester Spartans v North Park Vikings | L | 0-27 |
| NCAAF | 2022/11/12 18:30 | Anderson Ravens v Manchester Spartans | L | 19-12 |
| NCAAF | 2022/11/05 17:30 | Defiance Yellow Jackets v Manchester Spartans | L | 24-21 |
| NCAAF | 2022/10/29 17:30 | Manchester Spartans v Franklin College Grizzlies | L | 6-24 |
| NCAAF | 2022/10/22 17:30 | Manchester Spartans v Bluffton Beavers | L | 44-46 |
| NCAAF | 2022/10/15 17:30 | Manchester Spartans v Hanover | L | 20-51 |
| NCAAF | 2022/10/08 18:00 | Rose Hulman Engineers v Manchester Spartans | L | 48-14 |
| NCAAF | 2023/09/09 17:00 | Adrian Bulldogs v Defiance Yellow Jackets | W | 17-34 |
| NCAAF | 2023/09/02 17:30 | Defiance Yellow Jackets v Mount Union | L | 6-45 |
| NCAAF | 2022/11/12 18:30 | Bluffton Beavers v Defiance Yellow Jackets | W | 14-17 |
| NCAAF | 2022/11/05 17:30 | Defiance Yellow Jackets v Manchester Spartans | W | 24-21 |
| NCAAF | 2022/10/29 17:30 | Rose Hulman Engineers v Defiance Yellow Jackets | L | 76-35 |
| NCAAF | 2022/10/22 17:30 | Defiance Yellow Jackets v Anderson Ravens | W | 32-22 |
| NCAAF | 2022/10/15 17:30 | Franklin College Grizzlies v Defiance Yellow Jackets | L | 48-19 |
| NCAAF | 2022/10/08 17:30 | Mount St. Joseph Lions v Defiance Yellow Jackets | L | 55-35 |