Stadium: Cheek Field and Farris Stadium Round: 1
| NCAAF | 2022/11/05 18:00 | Birmingham Southern Panthers v Centre Colonels | L | 42-21 |
| NCAAF | 2021/10/16 17:00 | Centre Colonels v Birmingham Southern Panthers | L | 21-28 |
| NCAAF | 2019/10/26 17:00 | Centre Colonels v Birmingham Southern Panthers | L | 21-38 |
| NCAAF | 2018/11/10 19:00 | Birmingham Southern Panthers v Centre Colonels | W | 20-56 |
| NCAAF | 2022/11/12 18:00 | Centre Colonels v Millsaps Majors | W | 57-3 |
| NCAAF | 2022/11/05 18:00 | Birmingham Southern Panthers v Centre Colonels | L | 42-21 |
| NCAAF | 2022/10/29 16:00 | Centre Colonels v Trinity Tigers | L | 21-41 |
| NCAAF | 2022/10/22 18:00 | Hendrix Warriors v Centre Colonels | W | 42-45 |
| NCAAF | 2022/10/15 17:00 | Centre Colonels v Berry Vikings | L | 30-31 |
| NCAAF | 2022/10/08 17:00 | Centre Colonels v Sewanee Tigers | W | 35-16 |
| NCAAF | 2022/10/01 18:00 | Rhodes Lynx v Centre Colonels | W | 7-21 |
| NCAAF | 2022/09/24 18:30 | Trine Thunder v Centre Colonels | L | 17-0 |
| NCAAF | 2022/11/12 19:00 | Rhodes Lynx v Birmingham Southern Panthers | L | 20-3 |
| NCAAF | 2022/11/05 18:00 | Birmingham Southern Panthers v Centre Colonels | W | 42-21 |
| NCAAF | 2022/10/29 18:00 | Birmingham Southern Panthers v Hendrix Warriors | W | 30-7 |
| NCAAF | 2022/10/22 23:00 | Sewanee Tigers v Birmingham Southern Panthers | W | 3-47 |
| NCAAF | 2022/10/15 21:00 | Birmingham Southern Panthers v Millsaps Majors | W | 28-0 |
| NCAAF | 2022/10/08 18:00 | Trinity Tigers v Birmingham Southern Panthers | L | 23-20 |
| NCAAF | 2022/10/01 23:00 | Birmingham Southern Panthers v Berry Vikings | W | 24-10 |
| NCAAF | 2022/09/24 23:00 | Birmingham Southern Panthers v Point University Skyhawks | W | 34-14 |