Head to Head
| England EFL Trophy | 2021/11/30 19:00 | Leyton Orient v Milton Keynes Dons | D | 0-0 |
| England EFL Cup | 2015/08/11 18:45 | Milton Keynes Dons v Leyton Orient | W | 2-1 |
| England League 1 | 2015/04/18 14:00 | Milton Keynes Dons v Leyton Orient | W | 6-1 |
| England League 1 | 2014/10/18 14:00 | Leyton Orient v Milton Keynes Dons | D | 0-0 |
Home History
| England League 2 | 2024/05/11 18:45 | Milton Keynes Dons v Crawley Town | L | 1-5 |
| England League 2 | 2024/05/07 18:30 | Crawley Town v Milton Keynes Dons | L | 3-0 |
| England League 2 | 2024/04/27 14:00 | Milton Keynes Dons v Sutton Utd | D | 4-4 |
| England League 2 | 2024/04/20 14:00 | Harrogate Town v Milton Keynes Dons | W | 3-5 |
| England League 2 | 2024/04/13 14:00 | Milton Keynes Dons v Mansfield | L | 1-4 |
| England League 2 | 2024/04/06 14:00 | Forest Green v Milton Keynes Dons | W | 0-2 |
| England League 2 | 2024/04/01 14:00 | Notts County v Milton Keynes Dons | D | 3-3 |
| England League 2 | 2024/03/29 15:00 | Milton Keynes Dons v Walsall | W | 5-0 |
Away History
| England League 1 | 2024/04/27 11:30 | Shrewsbury v Leyton Orient | W | 1-3 |
| England League 1 | 2024/04/20 14:00 | Leyton Orient v Fleetwood Town | L | 0-1 |
| England League 1 | 2024/04/13 14:00 | Derby v Leyton Orient | L | 3-0 |
| England League 1 | 2024/04/09 18:45 | Leyton Orient v Exeter | D | 2-2 |
| England League 1 | 2024/04/06 14:00 | Leyton Orient v Cheltenham | W | 3-1 |
| England League 1 | 2024/04/01 14:00 | Leyton Orient v Peterborough | L | 1-2 |
| England League 1 | 2024/03/29 15:00 | Lincoln City v Leyton Orient | L | 1-0 |
| England League 1 | 2024/03/16 15:00 | Stevenage v Leyton Orient | W | 0-1 |