Head to Head
| England EFL Trophy | 2021/11/30 19:00 | Leyton Orient v Milton Keynes Dons | D | 0-0 |
| England EFL Cup | 2015/08/11 18:45 | Milton Keynes Dons v Leyton Orient | W | 2-1 |
| England League 1 | 2015/04/18 14:00 | Milton Keynes Dons v Leyton Orient | W | 6-1 |
| England League 1 | 2014/10/18 14:00 | Leyton Orient v Milton Keynes Dons | D | 0-0 |
Home History
| England League 2 | 2024/10/12 14:00 | Milton Keynes Dons v Port Vale | L | 0-1 |
| England EFL Trophy | 2024/10/08 18:00 | Milton Keynes Dons v Arsenal U21 | D | 2-2 |
| England League 2 | 2024/10/05 14:00 | Milton Keynes Dons v Tranmere | D | 1-1 |
| England League 2 | 2024/10/01 18:45 | Harrogate Town v Milton Keynes Dons | W | 1-5 |
| England League 2 | 2024/09/28 14:00 | Bromley v Milton Keynes Dons | D | 1-1 |
| England League 2 | 2024/09/21 14:00 | Milton Keynes Dons v Doncaster | D | 1-1 |
| England EFL Trophy | 2024/09/17 18:45 | Colchester v Milton Keynes Dons | L | 2-1 |
| England League 2 | 2024/09/14 11:30 | AFC Wimbledon v Milton Keynes Dons | L | 3-0 |
Away History
| England EFL Trophy | 2024/10/08 18:00 | Leyton Orient v Colchester | D | 1-1 |
| England League 1 | 2024/10/05 14:00 | Lincoln City v Leyton Orient | L | 2-1 |
| England League 1 | 2024/10/01 18:45 | Leyton Orient v Exeter | L | 0-1 |
| England League 1 | 2024/09/28 14:00 | Leyton Orient v Wrexham | D | 0-0 |
| England League 1 | 2024/09/24 18:45 | Leyton Orient v Peterborough | D | 2-2 |
| England League 1 | 2024/09/21 14:00 | Stockport v Leyton Orient | W | 1-4 |
| England EFL Cup | 2024/09/17 18:45 | Brentford v Leyton Orient | L | 3-1 |
| England League 1 | 2024/09/14 14:00 | Reading v Leyton Orient | W | 0-1 |