Stadium: Cardinal Stadium Round: 1
| NCAAF | 2023/11/11 18:00 | Catholic Cardinals v Juniata Eagles | W | 34-20 |
| NCAAF | 2023/11/04 16:00 | Wilkes Colonels v Catholic Cardinals | W | 35-40 |
| NCAAF | 2023/10/28 16:00 | Keystone Giants v Catholic Cardinals | W | 14-26 |
| NCAAF | 2023/10/14 17:00 | Catholic Cardinals v Lycoming Warriors | L | 25-28 |
| NCAAF | 2023/10/07 16:00 | Catholic Cardinals v Moravian Greyhounds | L | 28-36 |
| NCAAF | 2023/09/30 17:00 | Susquehanna Crusaders v Catholic Cardinals | L | 50-21 |
| NCAAF | 2023/09/23 17:00 | Catholic Cardinals v Alfred Saxons | L | 6-9 |
| NCAAF | 2023/09/16 16:00 | Morrisville State Mustangs v Catholic Cardinals | W | 20-31 |
| NCAAF | 2023/11/11 17:00 | Moravian Greyhounds v Wilkes Colonels | W | 6-41 |
| NCAAF | 2023/11/04 16:00 | Wilkes Colonels v Catholic Cardinals | L | 35-40 |
| NCAAF | 2023/10/21 17:00 | Susquehanna Crusaders v Wilkes Colonels | L | 34-7 |
| NCAAF | 2023/10/14 16:00 | Wilkes Colonels v Keystone Giants | W | 42-7 |
| NCAAF | 2023/10/07 16:00 | Lycoming Warriors v Wilkes Colonels | W | 35-48 |
| NCAAF | 2023/09/30 16:00 | Wilkes Colonels v Juniata Eagles | W | 63-14 |
| NCAAF | 2023/09/23 20:00 | St John Fisher Cardinals v Wilkes Colonels | L | 29-20 |
| NCAAF | 2023/09/16 16:00 | Wilkes Colonels v Brockport Golden Eagles | L | 7-31 |