[26] DET Red Wings 2-1 BUF Sabres [25] 2016-11-07 18:00
Stadium: First Niagara Center Round: 1
Home History
| NHL | 2016/11/06 21:50 | EDM Oilers v DET Red Wings | L | 2-1 |
| NHL | 2016/11/04 23:30 | WPG Jets v DET Red Wings | L | 5-3 |
| NHL | 2016/11/03 00:00 | DET Red Wings v PHI Flyers | L | 3-4 |
| NHL | 2016/10/30 20:49 | FLA Panthers v DET Red Wings | L | 5-2 |
| NHL | 2016/10/29 22:50 | BOS Bruins v DET Red Wings | L | 1-0 |
| NHL | 2016/10/28 00:00 | DET Red Wings v STL Blues | W | 2-1 |
| NHL | 2016/10/25 23:30 | CAR Hurricanes v DET Red Wings | W | 2-4 |
| NHL | 2016/10/22 23:00 | SJ Sharks v DET Red Wings | W | 0-3 |
Away History
| NHL | 2016/11/05 23:00 | BUF Sabres v OTT Senators | W | 2-1 |
| NHL | 2016/11/03 23:00 | TOR Maple Leafs v BUF Sabres | L | 2-1 |
| NHL | 2016/11/01 23:49 | BUF Sabres v MIN Wild | W | 2-1 |
| NHL | 2016/10/30 18:49 | BUF Sabres v WPG Jets | W | 3-1 |
| NHL | 2016/10/29 16:53 | FLA Panthers v BUF Sabres | W | 0-3 |
| NHL | 2016/10/27 23:00 | MIN Wild v BUF Sabres | L | 4-0 |
| NHL | 2016/10/25 23:30 | BUF Sabres v PHI Flyers | L | 3-4 |
| NHL | 2016/10/21 02:00 | BUF Sabres v VAN Canucks | L | 1-2 |