[14] Club Deportes Santa Cruz 1-2 Cobreloa [6] 2025-08-24 02:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 26
Head to Head
| Chile Primera B | 2025/05/23 22:00 | Cobreloa v Club Deportes Santa Cruz | D | 1-1 |
| Chile Primera B | 2023/09/21 21:30 | Cobreloa v Club Deportes Santa Cruz | L | 2-0 |
| Chile Primera B | 2023/04/23 16:30 | Club Deportes Santa Cruz v Cobreloa | D | 1-1 |
| Chile Primera B | 2022/08/01 00:30 | Club Deportes Santa Cruz v Cobreloa | D | 1-1 |
| Chile Primera B | 2022/06/02 19:00 | Cobreloa v Club Deportes Santa Cruz | L | 1-0 |
| Chile Primera B | 2021/11/06 23:30 | Club Deportes Santa Cruz v Cobreloa | D | 2-2 |
| Chile Primera B | 2021/08/08 15:00 | Cobreloa v Club Deportes Santa Cruz | W | 0-1 |
| Chile Primera B | 2020/12/10 13:00 | Club Deportes Santa Cruz v Cobreloa | W | 4-1 |
Home History
| Chile Primera B | 2025/08/15 19:00 | Santiago Morning v Club Deportes Santa Cruz | W | 0-1 |
| Chile Primera B | 2025/08/09 19:00 | Club Deportes Santa Cruz v Universidad de Concepcion | L | 1-2 |
| Chile Primera B | 2025/08/04 23:30 | Deportes Concepcion v Club Deportes Santa Cruz | L | 1-0 |
| Chile Primera B | 2025/07/26 16:30 | Club Deportes Santa Cruz v San Luis Quillota | D | 2-2 |
| Chile Primera B | 2025/07/19 19:00 | Club Deportes Santa Cruz v Deportes Recoleta | D | 0-0 |
| Chile Primera B | 2025/07/12 19:00 | Rangers de Talca v Club Deportes Santa Cruz | D | 2-2 |
| Chile Primera B | 2025/07/05 16:00 | Club Deportes Santa Cruz v Deportes Temuco | W | 2-0 |
| Chile Primera B | 2025/06/22 16:30 | Club Deportes Santa Cruz v CD Antofagasta | W | 3-0 |
Away History
| Chile Primera B | 2025/08/17 19:00 | Magallanes v Cobreloa | W | 3-4 |
| Chile Primera B | 2025/08/10 16:30 | CD Antofagasta v Cobreloa | L | 3-0 |
| Chile Primera B | 2025/08/02 19:00 | Cobreloa v Rangers de Talca | W | 4-1 |
| Chile Primera B | 2025/07/26 23:00 | Universidad de Concepcion v Cobreloa | W | 0-1 |
| Chile Primera B | 2025/07/19 16:30 | Cobreloa v San Marcos De Arica | W | 2-0 |
| Chile Primera B | 2025/07/12 16:00 | Union San Felipe v Cobreloa | L | 3-0 |
| Chile Primera B | 2025/07/06 16:30 | Cobreloa v Santiago Morning | L | 0-1 |
| Chile Cup | 2025/07/02 00:30 | Deportes Limache v Cobreloa | L | 3-0 |