Houston 42-20 East Carolina 2018-05-20 17:00
Stadium: Bagwell Field at Dowdy-Ficklen Stadium Round: 1
Home Manager: Scottie Montgomery Away Manager: Major Applewhite
Head to Head
| NCAAF | 2017/11/04 16:00 | East Carolina v Houston | W | 27-52 |
| NCAAF | 2012/11/03 12:00 | East Carolina v Houston | L | 48-28 |
| NCAAF | 2011/10/08 12:00 | Houston v East Carolina | W | 56-3 |
| NCAAF | 2009/12/05 12:00 | East Carolina v Houston | L | 38-32 |
| NCAAF | 2008/09/27 12:00 | East Carolina v Houston | W | 24-41 |
| NCAAF | 2007/09/29 12:00 | Houston v East Carolina | L | 35-37 |
| NCAAF | 2004/11/06 12:00 | Houston v East Carolina | W | 34-24 |
| NCAAF | 2003/09/30 12:00 | East Carolina v Houston | W | 13-27 |
Home History
| NCAAF | 2017/12/25 01:30 | Houston v Fresno State | L | 27-33 |
| NCAAF | 2017/11/24 17:00 | Navy v Houston | W | 14-24 |
| NCAAF | 2017/11/18 21:00 | Houston v Tulane | L | 17-20 |
| NCAAF | 2017/11/04 16:00 | East Carolina v Houston | W | 27-52 |
| NCAAF | 2017/10/28 19:45 | Houston v South Florida | W | 28-24 |
| NCAAF | 2017/10/20 00:00 | Memphis v Houston | L | 42-38 |
| NCAAF | 2017/10/14 20:00 | Houston v Tulsa | L | 17-45 |
| NCAAF | 2017/10/07 23:00 | Houston v SMU | W | 35-22 |
Away History
| NCAAF | 2017/11/25 17:00 | East Carolina v Memphis | L | 13-70 |
| NCAAF | 2017/11/18 17:00 | Cincinnati v East Carolina | W | 20-48 |
| NCAAF | 2017/11/12 00:00 | East Carolina v Tulane | L | 24-31 |
| NCAAF | 2017/11/04 16:00 | East Carolina v Houston | L | 27-52 |
| NCAAF | 2017/10/21 23:00 | BYU v East Carolina | W | 17-33 |
| NCAAF | 2017/10/14 23:00 | Central Florida v East Carolina | L | 63-21 |
| NCAAF | 2017/10/07 16:00 | Temple v East Carolina | L | 34-10 |
| NCAAF | 2017/09/30 16:00 | East Carolina v South Florida | L | 31-61 |