Head to Head
| NCAAF | 2023/09/05 00:00 | Clemson v Duke | L | 7-28 |
| NCAAF | 2018/11/18 00:00 | Duke v Clemson | W | 6-35 |
| NCAAF | 2012/11/03 12:00 | Duke v Clemson | W | 20-56 |
| NCAAF | 2008/11/15 12:00 | Clemson v Duke | W | 31-7 |
| NCAAF | 2007/11/03 12:00 | Duke v Clemson | W | 10-47 |
| NCAAF | 2005/11/05 12:00 | Clemson v Duke | W | 49-20 |
| NCAAF | 2004/11/13 12:00 | Duke v Clemson | L | 16-13 |
| NCAAF | 2003/11/15 12:00 | Clemson v Duke | W | 40-7 |
Home History
| NCAAF | 2024/12/21 21:00 | Clemson v Texas | L | 24-38 |
| NCAAF | 2024/12/08 01:00 | Clemson v SMU | W | 34-31 |
| NCAAF | 2024/11/30 17:00 | South Carolina v Clemson | L | 17-14 |
| NCAAF | 2024/11/23 20:30 | The Citadel v Clemson | W | 14-51 |
| NCAAF | 2024/11/16 17:00 | Clemson v Pittsburgh | W | 24-20 |
| NCAAF | 2024/11/09 20:30 | Clemson v Virginia Tech | W | 24-14 |
| NCAAF | 2024/11/02 23:30 | Louisville v Clemson | L | 33-21 |
| NCAAF | 2024/10/19 16:00 | Virginia v Clemson | W | 31-48 |
Away History
| NCAAF Bowl Games | 2025/01/03 01:00 | Duke v Mississippi | L | 20-52 |
| NCAAF | 2024/11/30 17:00 | Duke v Wake Forest | W | 23-17 |
| NCAAF | 2024/11/24 01:00 | Virginia Tech v Duke | W | 28-31 |
| NCAAF | 2024/11/09 20:30 | Duke v NC State | W | 29-19 |
| NCAAF | 2024/11/02 16:00 | Duke v Miami Florida | L | 31-53 |
| NCAAF | 2024/10/27 00:00 | SMU v Duke | L | 28-27 |
| NCAAF | 2024/10/18 23:00 | Florida State v Duke | W | 16-23 |
| NCAAF | 2024/10/06 00:00 | Duke v Georgia Tech | L | 14-24 |