[15] NY Islanders 3-1 BUF Sabres [8] 2018-09-08 19:00
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: Barry Trotz
Head to Head
| NHL | 2018/02/09 00:00 | NY Islanders v BUF Sabres | L | 3-4 |
| NHL | 2017/12/28 00:00 | BUF Sabres v NY Islanders | W | 2-3 |
| NHL | 2017/10/07 23:00 | NY Islanders v BUF Sabres | W | 6-3 |
| NHL Pre-Season | 2017/09/29 23:00 | NY Islanders v BUF Sabres | W | 3-1 |
| NHL | 2017/04/02 19:00 | NY Islanders v BUF Sabres | W | 4-2 |
| NHL | 2016/12/24 00:00 | BUF Sabres v NY Islanders | W | 1-5 |
| NHL | 2016/12/17 00:00 | NY Islanders v BUF Sabres | L | 2-3 |
Home History
| NHL | 2018/04/07 23:00 | NY Islanders v DET Red Wings | W | 4-3 |
| NHL | 2018/04/05 23:00 | NY Rangers v NY Islanders | W | 1-2 |
| NHL | 2018/04/03 23:00 | PHI Flyers v NY Islanders | W | 4-5 |
| NHL | 2018/03/31 23:00 | NY Islanders v NJ Devils | L | 3-4 |
| NHL | 2018/03/30 23:00 | TOR Maple Leafs v NY Islanders | L | 5-4 |
| NHL | 2018/03/27 23:30 | NY Islanders v OTT Senators | W | 4-3 |
| NHL | 2018/03/26 23:00 | FLA Panthers v NY Islanders | L | 3-0 |
| NHL | 2018/03/24 23:00 | CHI Blackhawks v NY Islanders | L | 3-1 |
Away History
| NHL | 2018/04/07 23:00 | BUF Sabres v FLA Panthers | L | 3-4 |
| NHL | 2018/04/06 23:30 | BUF Sabres v TB Lightning | L | 5-7 |
| NHL | 2018/04/04 23:30 | OTT Senators v BUF Sabres | L | 4-2 |
| NHL | 2018/04/02 23:00 | BUF Sabres v TOR Maple Leafs | L | 2-5 |
| NHL | 2018/04/01 00:00 | BUF Sabres v NSH Predators | W | 7-4 |
| NHL | 2018/03/29 23:00 | DET Red Wings v BUF Sabres | L | 6-3 |
| NHL | 2018/03/26 23:00 | BUF Sabres v TOR Maple Leafs | W | 3-2 |
| NHL | 2018/03/24 23:00 | BUF Sabres v NY Rangers | L | 1-5 |