Head to Head
| NFL | 2021/10/25 00:20 | IND Colts v SF 49ers | L | 30-18 |
| NFL Preseason | 2018/08/25 20:30 | SF 49ers v IND Colts | L | 17-23 |
| NFL | 2017/10/08 17:00 | SF 49ers v IND Colts | L | 23-26 |
Home History
| NFL | 2025/10/12 20:25 | SF 49ers v TB Buccaneers | L | 19-30 |
| NFL | 2025/10/03 00:15 | SF 49ers v LA Rams | W | 26-23 |
| NFL | 2025/09/28 20:05 | JAX Jaguars v SF 49ers | L | 26-21 |
| NFL | 2025/09/21 20:25 | ARZ Cardinals v SF 49ers | W | 15-16 |
| NFL | 2025/09/14 17:00 | SF 49ers v NO Saints | W | 26-21 |
| NFL | 2025/09/07 20:05 | SF 49ers v SEA Seahawks | W | 17-13 |
| NFL Preseason | 2025/08/24 00:30 | LA Chargers v SF 49ers | W | 23-30 |
| NFL Preseason | 2025/08/16 20:00 | SF 49ers v LV Raiders | W | 22-19 |
Away History
| NFL | 2025/10/12 17:00 | ARZ Cardinals v IND Colts | W | 27-31 |
| NFL | 2025/10/05 17:00 | LV Raiders v IND Colts | W | 6-40 |
| NFL | 2025/09/28 20:05 | IND Colts v LA Rams | L | 20-27 |
| NFL | 2025/09/21 17:00 | IND Colts v TEN Titans | W | 41-20 |
| NFL | 2025/09/14 20:05 | DEN Broncos v IND Colts | W | 28-29 |
| NFL | 2025/09/07 17:00 | MIA Dolphins v IND Colts | W | 8-33 |
| NFL Preseason | 2025/08/23 17:00 | IND Colts v CIN Bengals | W | 41-14 |
| NFL Preseason | 2025/08/16 17:00 | GB Packers v IND Colts | L | 23-19 |