Head to Head
| Ghana Premier League | 2025/06/01 15:00 | Asante Kotoko v Medeama SC | W | 3-2 |
| Ghana Premier League | 2025/01/05 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| World Club Friendlies | 2024/08/16 17:00 | Medeama SC v Asante Kotoko | L | 2-1 |
| Ghana Premier League | 2024/04/27 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2023/11/19 15:00 | Asante Kotoko v Medeama SC | W | 1-0 |
| Ghana Premier League | 2023/03/26 18:00 | Asante Kotoko v Medeama SC | L | 0-2 |
| Ghana Premier League | 2022/11/12 15:00 | Medeama SC v Asante Kotoko | W | 0-1 |
| Ghana Premier League | 2022/05/29 15:00 | Medeama SC v Asante Kotoko | W | 0-2 |
| Ghana Premier League | 2022/01/23 15:00 | Asante Kotoko v Medeama SC | W | 1-0 |
| Ghana Premier League | 2021/04/24 15:00 | Asante Kotoko v Medeama SC | L | 1-2 |
| Ghana Premier League | 2020/12/27 15:00 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2020/01/15 15:00 | Medeama SC v Asante Kotoko | L | 1-0 |
| Ghana Premier League | 2018/03/28 15:00 | Medeama SC v Asante Kotoko | L | 1-0 |
| Ghana FA Cup | 2017/10/02 15:00 | Asante Kotoko v Medeama SC | W | 1-0 |
| Ghana FA Cup | 2017/10/01 18:00 | Asante Kotoko v Medeama SC | D | 0-0 |
| Ghana Premier League | 2017/07/09 15:00 | Asante Kotoko v Medeama SC | W | 3-1 |
| Ghana Premier League | 2017/04/05 15:00 | Medeama SC v Asante Kotoko | L | 2-1 |
| Ghana Premier League | 2016/09/11 15:15 | Medeama SC v Asante Kotoko | D | 1-1 |
| Ghana Premier League | 2016/03/06 15:15 | Asante Kotoko v Medeama SC | D | 2-2 |
| Ghana FA Cup | 2015/08/30 17:00 | Asante Kotoko v Medeama SC | L | 1-2 |
| Ghana Premier League | 2015/07/05 15:00 | Medeama SC v Asante Kotoko | D | 0-0 |
| Ghana Premier League | 2015/03/08 15:00 | Asante Kotoko v Medeama SC | D | 1-1 |