[14] BUF Sabres 3-2 OTT Senators [17] 2025-10-12 02:00
Stadium: Canadian Tire Centre
Home Manager: Lindy Ruff Away Manager: Travis Green
Head to Head
| NHL | 2025/04/01 23:00 | BUF Sabres v OTT Senators | W | 5-2 |
| NHL | 2025/03/25 23:00 | OTT Senators v BUF Sabres | W | 2-3 |
| NHL | 2025/01/10 00:00 | BUF Sabres v OTT Senators | W | 4-0 |
| NHL | 2024/11/06 00:00 | OTT Senators v BUF Sabres | W | 1-5 |
| NHL Pre-Season | 2024/09/26 23:00 | BUF Sabres v OTT Senators | W | 3-2 |
| NHL | 2024/03/27 23:00 | OTT Senators v BUF Sabres | L | 6-2 |
| NHL | 2024/01/12 00:00 | OTT Senators v BUF Sabres | W | 3-5 |
| NHL | 2023/12/31 23:00 | BUF Sabres v OTT Senators | L | 1-5 |
| NHL | 2023/10/24 22:45 | BUF Sabres v OTT Senators | W | 6-4 |
| NHL | 2023/04/13 23:00 | OTT Senators v BUF Sabres | W | 3-4 |
| NHL | 2023/01/02 00:00 | BUF Sabres v OTT Senators | L | 1-3 |
| NHL | 2022/11/17 00:00 | BUF Sabres v OTT Senators | L | 1-4 |
| NHL | 2022/10/13 23:00 | OTT Senators v BUF Sabres | W | 1-4 |
| NHL | 2022/02/18 00:00 | OTT Senators v BUF Sabres | L | 3-1 |
| NHL | 2022/01/26 00:00 | BUF Sabres v OTT Senators | L | 0-5 |
| NHL | 2022/01/19 00:00 | BUF Sabres v OTT Senators | W | 3-1 |
| NHL | 2020/02/19 00:30 | BUF Sabres v OTT Senators | L | 4-7 |
| NHL | 2020/01/29 00:00 | OTT Senators v BUF Sabres | L | 5-2 |
| NHL | 2019/12/24 00:30 | BUF Sabres v OTT Senators | L | 1-3 |
| NHL | 2019/11/17 00:00 | OTT Senators v BUF Sabres | W | 2-4 |
| NHL | 2019/04/04 23:00 | OTT Senators v BUF Sabres | W | 2-5 |
| NHL | 2019/03/26 23:30 | BUF Sabres v OTT Senators | L | 0-4 |
| NHL | 2018/11/03 18:00 | OTT Senators v BUF Sabres | W | 2-9 |
| NHL | 2018/11/01 23:30 | BUF Sabres v OTT Senators | L | 2-4 |
| NHL | 2018/04/04 23:30 | OTT Senators v BUF Sabres | L | 4-2 |
| NHL | 2018/03/09 00:30 | BUF Sabres v OTT Senators | W | 4-3 |
| NHL | 2018/02/16 00:30 | BUF Sabres v OTT Senators | L | 2-3 |
| NHL | 2017/12/13 00:00 | OTT Senators v BUF Sabres | W | 2-3 |
| NHL | 2017/02/15 00:30 | BUF Sabres v OTT Senators | W | 3-2 |
| NHL | 2017/02/05 00:00 | OTT Senators v BUF Sabres | W | 0-4 |