[18] Cologne II 1-3 Schalke II [8] 2022-05-04 14:00
Stadium: Franz-Kremer-Stadion Round: 2
Referee: Fasihullah Habibi Home Manager: Mark Zimmermann Away Manager: Torsten Frohling
Head to Head
| Germany Regionalliga West | 2021/12/13 13:00 | Cologne II v Schalke II | W | 2-1 |
| Germany Regionalliga West | 2021/08/15 13:00 | Schalke II v Cologne II | W | 1-2 |
| Germany Regionalliga West | 2021/03/20 14:30 | Cologne II v Schalke II | W | 5-2 |
| Germany Regionalliga West | 2020/10/21 17:30 | Schalke II v Cologne II | L | 3-0 |
| Germany Regionalliga West | 2019/11/09 13:00 | Cologne II v Schalke II | W | 3-0 |
| Germany Regionalliga West | 2016/12/03 13:00 | Cologne II v Schalke II | W | 2-1 |
| Germany Regionalliga West | 2016/08/05 12:00 | Schalke II v Cologne II | W | 0-1 |
| Germany Regionalliga West | 2016/03/11 18:30 | Cologne II v Schalke II | L | 0-1 |
| Germany Regionalliga West | 2015/09/19 12:00 | Schalke II v Cologne II | D | 1-1 |
| Germany Regionalliga West | 2015/03/27 13:00 | Cologne II v Schalke II | L | 1-4 |
| Germany Regionalliga West | 2014/09/27 11:00 | Schalke II v Cologne II | D | 1-1 |