[14] Rio Ave 1-0 Santa Clara [15] 2022-06-12 12:30
Stadium: Estadio dos Arcos Round: 8
Referee: Claudio Filipe Ruivo Pereira Home Manager: Luis Freire Away Manager: Mario Silva
Head to Head
| Portugal League Cup | 2021/09/22 18:00 | Rio Ave v Santa Clara | D | 2-2 |
| Portugal Primeira Liga | 2021/05/11 15:00 | Santa Clara v Rio Ave | L | 1-0 |
| Portugal Primeira Liga | 2021/01/25 16:30 | Rio Ave v Santa Clara | L | 1-2 |
| Portugal Primeira Liga | 2020/07/18 18:00 | Rio Ave v Santa Clara | D | 2-2 |
| Portugal Primeira Liga | 2020/01/10 19:00 | Santa Clara v Rio Ave | W | 0-1 |
| Europe Friendlies | 2019/07/20 17:30 | Rio Ave v Santa Clara | D | 1-1 |
| Portugal Primeira Liga | 2019/02/15 20:30 | Rio Ave v Santa Clara | L | 1-2 |
| Portugal Primeira Liga | 2018/09/22 15:30 | Santa Clara v Rio Ave | W | 1-3 |
| Portugal Cup | 2016/10/16 11:00 | Santa Clara v Rio Ave | L | 5-3 |