| NCAAF | 10/11 17:00 | 1 | Moravian Greyhounds v Wilkes Colonels | W | 7-26 | |
| NCAAF | 10/04 16:00 | 1 | Wilkes Colonels v Catholic Cardinals | W | 15-13 | |
| NCAAF | 09/27 21:00 | 1 | Montclair State Red Hawks v Wilkes Colonels | W | 21-24 | |
| NCAAF | 09/20 16:00 | 1 | Wilkes Colonels v Muhlenberg Mules | L | 18-26 | |
| NCAAF | 09/13 16:00 | 1 | Tcnj Lions v Wilkes Colonels | L | 17-3 | |
| NCAAF | 09/04 23:00 | 1 | Wilkes Colonels v Kings Monarchs | W | 19-16 | |
| NCAAF | 11/23 18:00 | 1 | Wilkes Colonels v Washington And Lee Generals | L | 21-40 | |
| NCAAF | 11/16 17:00 | - |
Wilkes Colonels v
Besiktas Women
|
W | 47-28 | |
| NCAAF | 11/09 18:00 | 1 | Catholic Cardinals v Wilkes Colonels | W | 15-40 | |
| NCAAF | 10/26 16:00 | - | Wilkes Colonels v Susquehanna Crusaders | L | 21-48 | |
| NCAAF | 10/19 16:00 | 1 | Keystone Giants v Wilkes Colonels | W | 24-69 | |
| NCAAF | 10/12 16:00 | - |
Wilkes Colonels v
Colliers Wood Utd
|
W | 53-28 | |
| NCAAF | 10/04 22:00 | - | Juniata Eagles v Wilkes Colonels | W | 7-54 | |
| NCAAF | 09/28 16:00 | - | Wilkes Colonels v St John Fisher Cardinals | W | 28-21 | |
| NCAAF | 09/21 17:00 | 1 | Brockport Golden Eagles v Wilkes Colonels | L | 31-17 | |
| NCAAF | 09/13 22:00 | - | Wilkes Colonels v Rpi Engineers | L | 25-32 | |
| NCAAF | 09/07 22:00 | 1 | Kings Monarchs v Wilkes Colonels | W | 28-43 | |
| NCAAF | 11/11 17:00 | 1 | Moravian Greyhounds v Wilkes Colonels | W | 6-41 | |
| NCAAF | 11/04 16:00 | 1 | Wilkes Colonels v Catholic Cardinals | L | 35-40 | |
| NCAAF | 10/21 17:00 | 1 | Middlesbrough Women v Wilkes Colonels | L | 34-7 | |
| NCAAF | 10/14 16:00 | 1 | Wilkes Colonels v Keystone Giants | W | 42-7 | |
| NCAAF | 10/07 16:00 | 1 | Lycoming Warriors v Wilkes Colonels | W | 35-48 | |
| NCAAF | 09/30 16:00 | 1 | Wilkes Colonels v Juniata Eagles | W | 63-14 | |
| NCAAF | 09/23 20:00 | 1 | St John Fisher Cardinals v Wilkes Colonels | L | 29-20 | |
| NCAAF | 09/16 16:00 | 1 | Wilkes Colonels v Brockport Golden Eagles | L | 7-31 | |
| NCAAF | 09/09 16:00 | 1 | Rpi Engineers v Wilkes Colonels | L | 38-14 | |
| NCAAF | 09/02 16:00 | 1 | Wilkes Colonels v Kings Monarchs | L | 23-27 | |
| NCAAF | 11/12 17:00 | 1 | Wilkes Colonels v Kings Monarchs | W | 58-42 | |
| NCAAF | 11/05 16:00 | 1 | Stevenson Mustangs v Wilkes Colonels | L | 28-0 | |
| NCAAF | 10/29 16:00 | 1 | Wilkes Colonels v Lycoming Warriors | W | 24-7 |
The Wilkes Colonels are a collegiate American football team representing Wilkes University in Wilkes-Barre, Pennsylvania. Competing in the NCAA Division III, the Colonels are known for their competitive spirit, strong team dynamics, and commitment to excellence on the gridiron. The team boasts a rich history of dedication and community support, emphasizing both athletic achievement and academic success. With a talented roster of student-athletes and experienced coaching staff, the Wilkes Colonels strive to excel in their conference and make a lasting impact in college football.