| NCAAF | 10/22 17:00 | 1 | Delaware Valley Aggies v Wilkes Colonels | L | 27-14 | |
| NCAAF | 10/15 16:00 | 1 | Wilkes Colonels v Misericordia Cougars | W | 28-0 | |
| NCAAF | 10/08 16:00 | 1 |
Alvernia Golden Wolves
v
Wilkes Colonels |
W | 14-35 | |
| NCAAF | 10/01 16:00 | 1 | Wilkes Colonels v Albright Lions | W | 27-0 | |
| NCAAF | 09/24 17:00 | 1 | Lebanon Valley Flying Dutchmen v Wilkes Colonels | L | 24-19 | |
| NCAAF | 09/17 16:00 | 1 | Wilkes Colonels v Widener Pride | W | 44-20 | |
| NCAAF | 09/03 17:00 | 1 | Keystone Giants v Wilkes Colonels | W | 21-48 | |
| NCAAF | 11/13 17:00 | 1 | Kings Monarchs v Wilkes Colonels | L | 34-7 | |
| NCAAF | 11/06 17:00 | 1 | Wilkes Colonels v Delaware Valley Aggies | L | 0-30 | |
| NCAAF | 10/30 17:00 | 1 | Lycoming Warriors v Wilkes Colonels | L | 30-27 | |
| NCAAF | 10/23 17:00 | 1 | Wilkes Colonels v Lebanon Valley Flying Dutchmen | W | 30-20 | |
| NCAAF | 10/16 17:00 | 1 | Widener Pride v Wilkes Colonels | L | 30-13 | |
| NCAAF | 10/09 16:00 | 1 | Albright Lions v Wilkes Colonels | W | 28-31 | |
| NCAAF | 10/02 16:00 | 1 | Wilkes Colonels v Stevenson Mustangs | W | 21-14 | |
| NCAAF | 09/25 17:00 | 1 |
Wilkes Colonels v
Alvernia Golden Wolves
|
W | 23-0 | |
| NCAAF | 09/18 17:00 | 1 | Misericordia Cougars v Wilkes Colonels | W | 15-35 | |
| NCAAF | 09/04 17:00 | 1 | Wilkes Colonels v Keystone Giants | W | 46-7 | |
| NCAAF | 11/16 17:00 | 1 | Kings Monarchs v Wilkes Colonels | W | 14-24 | |
| NCAAF | 11/09 17:00 | 1 | Wilkes Colonels v Stevenson Mustangs | L | 21-42 | |
| NCAAF | 11/02 17:00 | 1 | Wilkes Colonels v Fdu Florham Devils | W | 45-20 | |
| NCAAF | 10/26 17:00 | 1 | Misericordia Cougars v Wilkes Colonels | W | 35-36 | |
| NCAAF | 10/19 17:00 | 1 | Wilkes Colonels v Delaware Valley Aggies | L | 0-42 | |
| NCAAF | 10/12 17:00 | 1 | Albright Lions v Wilkes Colonels | W | 40-42 | |
| NCAAF | 10/05 17:00 | 1 |
Wilkes Colonels v
Alvernia Golden Wolves
|
W | 45-12 | |
| NCAAF | 09/21 17:00 | 1 | Lycoming Warriors v Wilkes Colonels | W | 17-24 | |
| NCAAF | 09/14 16:00 | 1 |
Wilkes Colonels v
Livorno
|
W | 30-24 | |
| NCAAF | 09/07 17:00 | 1 | Hartwick Hawks v Wilkes Colonels | W | 21-38 | |
| NCAAF | 11/10 17:00 | 1 | Wilkes Colonels v Kings Monarchs | L | 0-45 | |
| NCAAF | 10/27 17:00 | 1 | Wilkes Colonels v Lycoming Warriors | W | 14-7 | |
| NCAAF | 10/20 16:00 | 1 | Stevenson Mustangs v Wilkes Colonels | L | 33-21 |
The Wilkes Colonels are a collegiate American football team representing Wilkes University in Wilkes-Barre, Pennsylvania. Competing in the NCAA Division III, the Colonels are known for their competitive spirit, strong team dynamics, and commitment to excellence on the gridiron. The team boasts a rich history of dedication and community support, emphasizing both athletic achievement and academic success. With a talented roster of student-athletes and experienced coaching staff, the Wilkes Colonels strive to excel in their conference and make a lasting impact in college football.